The University Hospital Centre’s Supervisory Board and the Director General of the Regional Health Agency are informed without delay by the legal representatives mentioned in II of Article R. 6145-80 of any factor likely to have a lasting effect on the University Hospital Centre’s financial and asset situation as a result of the activity of the companies mentioned in Article R. 6145-74. The director of the university hospital centre immediately takes the measures required by this situation and informs the director general of the regional health agency.