The conference is chaired by a delegate for regional cooperation in the Antilles-Guyane zone, appointed by decree. It is made up of members of the management committees of the regional cooperation funds of Guadeloupe, French Guiana and Martinique, as well as representatives of the territorial councils of Saint-Barthélemy and Saint-Martin, appointed respectively by the presidents of each of the territorial councils.
The latter may hear any person whose hearing is deemed useful by the Chairman.